{"id":2005,"date":"2026-10-15T16:05:36","date_gmt":"2026-10-15T08:05:36","guid":{"rendered":"https:\/\/uredanaturals.com\/?post_type=product&p=2005"},"modified":"2026-10-15T16:07:02","modified_gmt":"2026-10-15T08:07:02","slug":"shikimic-acid","status":"publish","type":"product","link":"https:\/\/uredanaturals.com\/es\/producto\/shikimic-acid\/","title":{"rendered":"Shikimic Acid"},"content":{"rendered":"

Shikimic Acid from Ginkgo Biloba Leaves<\/h2>\n

Shikimic Acid is a defined organic acid supplied as a white powder and derived from Ginkgo biloba leaves. Ureda Naturals manufactures this water-soluble ingredient for pharmaceutical intermediate development, chiral synthesis and selected specialty formulation applications.<\/p>\n

The material is specified by assay on a dry basis, specific rotation, moisture, ash, melting point, heavy metals and water solubility. These attributes help buyers evaluate chemical identity, material consistency and suitability for downstream process development.<\/p>\n

Product Specifications<\/h2>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Test Item<\/th>\nSpecification<\/th>\n<\/tr>\n<\/thead>\n
Product Name<\/th>\nShikimic Acid<\/td>\n<\/tr>\n
Source<\/th>\nGinkgo biloba leaves<\/td>\n<\/tr>\n
CAS No.<\/th>\n138-59-0<\/td>\n<\/tr>\n
Appearance<\/th>\nWhite powder<\/td>\n<\/tr>\n
Shikimic Acid Assay, Dry Basis<\/th>\n\u226598.0%<\/td>\n<\/tr>\n
Moisture<\/th>\n\u22640.5%<\/td>\n<\/tr>\n
Specific Rotation [\u03b1]D25<\/sup><\/th>\n\u2212185\u00b0 to \u2212180\u00b0<\/td>\n<\/tr>\n
Ash<\/th>\n\u22640.5%<\/td>\n<\/tr>\n
Melting Point<\/th>\n184\u2013188\u00b0C<\/td>\n<\/tr>\n
Heavy Metals, as Pb<\/th>\n\u226420 mg\/kg<\/td>\n<\/tr>\n
Solubility<\/th>\nEasily soluble in water<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Defined Shikimic Acid, Not Standardized Ginkgo Extract<\/h2>\n

Shikimic Acid and standardized Ginkgo biloba extract are different commercial materials. A standardized Ginkgo extract is characterized by a broader botanical profile, while Shikimic Acid is supplied as a defined small-molecule organic acid with a dedicated assay and identity-control framework.<\/p>\n

This distinction is important when the ingredient is used as a process intermediate. Buyers should qualify the material against the intended chemical route and not substitute a general Ginkgo extract specification for a Shikimic Acid specification.<\/p>\n

Source and Purification Control<\/h2>\n

Ginkgo biloba leaves contain a complex matrix of flavonoids, terpene-related constituents and other organic compounds. Producing a defined Shikimic Acid material therefore requires separation of the target acid from the surrounding botanical matrix.<\/p>\n

The manufacturing route is organized around controlled extraction, clarification, selective separation, concentration, crystallization and drying. The resulting release profile focuses on the attributes most relevant to chemical identity and process use: dry-basis assay, optical rotation, moisture, ash, melting point, heavy metals and aqueous solubility.<\/p>\n

Quality Attributes for Process Qualification<\/h2>\n\n\n\n\n\n\n\n\n\n\n\n
Attribute<\/th>\nWhy It Matters to the Buyer<\/th>\n<\/tr>\n<\/thead>\n
Dry-basis assay<\/th>\nDefines the active Shikimic Acid fraction used for material comparison and charge calculation.<\/td>\n<\/tr>\n
Moisture<\/th>\nChanges the as-is mass required to deliver a defined dry-basis amount and can affect storage behavior.<\/td>\n<\/tr>\n
Specific rotation<\/th>\nProvides an orthogonal identity and stereochemical consistency check alongside the assay.<\/td>\n<\/tr>\n
Ash<\/th>\nIndicates the level of inorganic residue remaining in the material.<\/td>\n<\/tr>\n
Melting point<\/th>\nProvides an additional physical identity and solid-state consistency reference.<\/td>\n<\/tr>\n
Heavy metals<\/th>\nSupports raw-material screening and customer quality-release requirements.<\/td>\n<\/tr>\n
Water solubility<\/th>\nHelps determine the suitability of the material for aqueous reaction, dilution and formulation steps.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Dry-Basis Charge Calculation<\/h2>\n

When the customer\u2019s process requires a defined mass of Shikimic Acid, the powder charge should account for both assay and moisture:<\/p>\n

Powder charge = Target active mass \u00f7 [assay fraction \u00d7 (1 \u2212 moisture fraction)]<\/strong><\/p>\n

This calculation keeps the material addition aligned with the dry-basis specification rather than relying only on the gross powder weight.<\/p>\n

Applications<\/h2>\n

Pharmaceutical Intermediate Development<\/h3>\n

Shikimic Acid is used as a chiral starting material in pharmaceutical process development, including routes related to oseltamivir synthesis. The defined assay and optical rotation provide practical release attributes for route qualification and raw-material comparison.<\/p>\n

Chiral Synthesis and Process Chemistry<\/h3>\n

For research and manufacturing teams working with stereochemically defined intermediates, Shikimic Acid can be evaluated as a plant-derived building block. Assay, specific rotation, moisture and melting point should be considered together when comparing material lots or process trials.<\/p>\n

Water-Based Specialty Formulations<\/h3>\n

The material\u2019s water solubility supports evaluation in aqueous systems and water-based specialty formulations where a white, defined organic acid is required.<\/p>\n

Supply, Packaging and Technical Documents<\/h2>\n
    \n
  • MOQ:<\/strong> 1 kg<\/li>\n
  • Physical form:<\/strong> White powder<\/li>\n
  • Packaging:<\/strong> Aluminum-barrier inner bags and fiber drums in standard commercial formats<\/li>\n
  • Storage:<\/strong> Store in a cool, dry and sealed environment away from direct light<\/li>\n
  • Technical documents:<\/strong> COA, TDS and SDS available for product qualification and purchasing review<\/li>\n<\/ul>\n

    Technical FAQ<\/h2>\n
    \nWhy is Ginkgo biloba leaf-derived Shikimic Acid different from a standardized Ginkgo extract?<\/summary>\n

    A standardized Ginkgo extract is defined by a broader botanical composition, while Shikimic Acid is a specific small-molecule organic acid. The two materials therefore require different specifications, analytical controls and application decisions. A standardized Ginkgo extract should not be used as a substitute for a defined Shikimic Acid grade in a chemical synthesis route.<\/p>\n<\/details>\n

    \nWhat does specific rotation contribute to Shikimic Acid qualification?<\/summary>\n

    Specific rotation provides an additional identity and stereochemical consistency check beyond the assay. For process chemistry, it is most useful when reviewed together with assay, moisture, melting point and the customer\u2019s route-specific impurity requirements.<\/p>\n<\/details>\n

    \nHow should the dry-basis assay and moisture be used in charge calculation?<\/summary>\n

    The dry-basis assay expresses the Shikimic Acid content after excluding water. The actual powder charge must therefore account for both the assay fraction and the moisture fraction. Using only the gross powder weight can understate or overstate the amount of active material delivered to the process.<\/p>\n<\/details>\n

    \nWhy is melting point included alongside assay and optical rotation?<\/summary>\n

    Melting point provides a separate physical identity and solid-state reference. It does not replace chemical assay or optical rotation, but it adds another comparison point when investigating material consistency or an unexpected difference in dissolution or handling behavior.<\/p>\n<\/details>\n

    \nWhat should be evaluated before using Shikimic Acid in an aqueous process?<\/summary>\n

    Confirm the material identity, dry-basis charge, water addition sequence and the actual dissolution behavior under the process conditions. Temperature, concentration, mixing intensity and hold time can influence how quickly the material enters solution, so the customer\u2019s process should be qualified at the intended working concentration before scale-up.<\/p>\n<\/details>\n","protected":false},"excerpt":{"rendered":"

    Shikimic Acid is a Ginkgo biloba leaf-derived, water-soluble organic acid supplied as a white powder. Ureda Naturals offers this defined material with a dry-basis assay of \u226598.0%, specific rotation of \u2212185\u00b0 to \u2212180\u00b0, moisture \u22640.5% and ash \u22640.5% for pharmaceutical intermediate and specialty formulation development.<\/p>","protected":false},"featured_media":2006,"template":"","meta":[],"product_brand":[],"product_cat":[25],"product_tag":[217,216,215],"class_list":["post-2005","product","type-product","status-publish","has-post-thumbnail","product_cat-plant-extracts-botanical-ingredients","product_tag-cas-138-59-0","product_tag-ginkgo-biloba-derived-ingredient","product_tag-shikimic-acid","first","instock","shipping-taxable","product-type-simple"],"yoast_head":"\nShikimic Acid Manufacturer | Ureda Naturals<\/title>\n<meta name=\"description\" content=\"Ureda Naturals manufactures Ginkgo biloba leaf-derived Shikimic Acid, CAS 138-59-0, with \u226598.0% dry-basis assay and defined optical rotation.\" \/>\n<meta name=\"robots\" content=\"noindex, follow, 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