{"id":1816,"date":"2026-10-09T14:55:07","date_gmt":"2026-10-09T06:55:07","guid":{"rendered":"https:\/\/uredanaturals.com\/?post_type=product&p=1816"},"modified":"2026-10-09T14:58:39","modified_gmt":"2026-10-09T06:58:39","slug":"low-molecular-weight-chondroitin-sulfate-sodium","status":"publish","type":"product","link":"https:\/\/uredanaturals.com\/es\/producto\/low-molecular-weight-chondroitin-sulfate-sodium\/","title":{"rendered":"Low Molecular Weight Chondroitin Sulfate Sodium"},"content":{"rendered":"
\n

As a manufacturer of Low Molecular Weight Chondroitin Sulfate Sodium, Ureda Naturals supplies a powder grade with a standard molecular-weight specification of 3\u20135 kDa and customized molecular-weight specifications for different formulation targets.<\/p>\n

The product profile goes beyond a single molecular-weight figure. It features a narrow molecular-weight distribution, clear structural characterization and laboratory-verified activity. Compared with conventional chondroitin sulfate, the product is characterized by easier dissolution in water, easier digestion, absorption and utilization, reduced gastrointestinal irritation, and stronger anti-inflammatory, antioxidant and related biological activity.<\/p>\n

Molecular-Weight Specifications and Selection<\/h2>\n

Molecular weight may be expressed as a range, an average value or the proportion below a defined threshold. These descriptions are not interchangeable. When setting a purchase specification, identify the measurement format as well as the target value so that different grades can be compared on the same basis.<\/p>\n\n\n\n\n\n\n\n\n\n
Specification Option<\/th>\nMolecular-Weight Target<\/th>\nHow to Interpret It<\/th>\n<\/tr>\n<\/thead>\n
Standard low-molecular-weight grade<\/td>\n3\u20135 kDa<\/td>\nStandard grade; the COA table below corresponds to this specification.<\/td>\n<\/tr>\n
Customized molecular-weight range<\/td>\n<5 kDa<\/td>\nA range-based target. Confirm the measurement convention when defining the purchase specification.<\/td>\n<\/tr>\n
Customized molecular-weight range<\/td>\n5\u201315 kDa<\/td>\nA higher range option for projects requiring a different molecular-weight profile.<\/td>\n<\/tr>\n
Distribution-defined grade<\/td>\nFor example, \u226585% below 3 kDa<\/td>\nSpecifies the fraction below a threshold; it is not the same as an average molecular weight of 3 kDa.<\/td>\n<\/tr>\n
Ultra-low-molecular-weight chondroitin sulfate oligosaccharide<\/td>\n\u22641 kDa<\/td>\nA distinct ultra-low-molecular-weight option, separate from the standard 3\u20135 kDa grade.<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Standard 3\u20135 kDa Grade: Quality Specifications and COA Results<\/h2>\n

The following table presents the specification limits and COA results for the standard grade. Assay is calculated on the dried basis.<\/p>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Test Item<\/th>\nSpecification<\/th>\nResult<\/th>\n<\/tr>\n<\/thead>\n
Appearance<\/td>\nWhite or almost white powder<\/td>\nPass<\/td>\n<\/tr>\n
Clarity (420 nm)<\/td>\nAbsorbance \u22640.35<\/td>\n0.09<\/td>\n<\/tr>\n
Identification \u2014 liquid phase<\/td>\nConsistent with the retention time of the reference substance<\/td>\nPass<\/td>\n<\/tr>\n
Identification \u2014 IR spectrum<\/td>\nConsistent with the reference sample spectrum<\/td>\nPass<\/td>\n<\/tr>\n
Sodium salt reaction<\/td>\nPositive<\/td>\nPass<\/td>\n<\/tr>\n
pH value<\/td>\n5.5\u20137.5<\/td>\n6.3<\/td>\n<\/tr>\n
Chloride<\/td>\n\u22640.5%<\/td>\nPass<\/td>\n<\/tr>\n
Sulfate radical<\/td>\n\u22640.24%<\/td>\nPass<\/td>\n<\/tr>\n
Protein (dry basis)<\/td>\n\u22643.0%<\/td>\nPass<\/td>\n<\/tr>\n
Loss on drying<\/td>\n\u226410.0%<\/td>\n9.55%<\/td>\n<\/tr>\n
Residue on ignition<\/td>\n20.0\u201330.0%<\/td>\n25.90%<\/td>\n<\/tr>\n
Lead<\/td>\n\u22640.5 mg\/kg<\/td>\n<0.04 mg\/kg<\/td>\n<\/tr>\n
Total arsenic<\/td>\n\u22640.1 mg\/kg<\/td>\n<0.04 mg\/kg<\/td>\n<\/tr>\n
Total mercury<\/td>\n\u22640.1 mg\/kg<\/td>\n<0.01 mg\/kg<\/td>\n<\/tr>\n
Total bacterial count<\/td>\n\u22641,000 CFU\/g<\/td>\nPass<\/td>\n<\/tr>\n
Yeasts and molds<\/td>\n\u2264100 CFU\/g<\/td>\nPass<\/td>\n<\/tr>\n
Escherichia coli<\/em><\/td>\nNegative<\/td>\nNegative<\/td>\n<\/tr>\n
Salmonella<\/em> species<\/td>\nNegative<\/td>\nNegative<\/td>\n<\/tr>\n
Staphylococcus aureus<\/em> (\/25 g)<\/td>\nNegative<\/td>\nNot detected (Negative)<\/td>\n<\/tr>\n
Assay (calculated on the dried basis)<\/td>\n\u226590.0%<\/td>\n96.80%<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

How to Evaluate Molecular Weight, Assay and Clarity<\/h2>\n

Molecular weight describes the size profile; assay describes content<\/h3>\n

Molecular-weight specification and assay answer different questions. Assay reports the measured chondroitin sulfate content, while molecular-weight data describes the size profile of the material. Two ingredients with similar assay values may still have different molecular-weight distributions. For grade selection, compare the molecular-weight definition and distribution alongside assay rather than treating assay as a substitute for molecular-weight data.<\/p>\n

Read dried-basis assay together with loss on drying<\/h3>\n

The COA reports assay on a dried basis and separately reports loss on drying. These values describe different properties: dried-basis assay expresses content after the specified drying calculation, while loss on drying measures mass loss under the test conditions. Keep the reporting basis consistent when comparing supplier specifications or setting a formulation target.<\/p>\n

Use the clarity result as a starting point for beverage trials<\/h3>\n

The COA reports a clarity absorbance of 0.09 at 420 nm against a limit of \u22640.35. For a clear beverage, first assess the ingredient in the intended aqueous phase, then repeat the observation after adding the complete formula and applying the planned process. Salts, proteins and hydrocolloids can change the appearance of a finished system, so staged trials help identify when a change occurs.<\/p>\n

Interpret residue on ignition in context<\/h3>\n

The COA specifies residue on ignition at 20.0\u201330.0%, with a result of 25.90%. This is a separate quality parameter; it should not be read as an organic-impurity percentage. Review it alongside assay, identification, chloride and sulfate results for a more complete quality assessment.<\/p>\n

Formulation Applications<\/h2>\n

Nutraceuticals, tablets, capsules and powder blends<\/h3>\n

For solid dosage forms, the lower-molecular-weight profile and water solubility can support ingredient handling and dissolution planning. During development, evaluate powder flow, blend uniformity and dissolution in the actual excipient system. A water-solubility result alone does not establish how a powder blend will flow or perform in a finished dosage form.<\/p>\n

Functional foods and beverages<\/h3>\n

For aqueous products, begin with the intended use level in the target water phase and record dissolution and appearance. Then add the complete beverage matrix and assess the product after processing and storage. This sequence helps distinguish initial dissolution behavior from changes introduced by the finished formula.<\/p>\n

Cosmetic formulations<\/h3>\n

For cosmetic applications, assess dissolution, appearance and compatibility in the intended formula. The molecular-weight specification helps define the ingredient grade, while the finished formula determines its practical incorporation and final appearance.<\/p>\n

Supply, Packaging and Storage<\/h2>\n
    \n
  • Standard molecular-weight specification: 3\u20135 kDa<\/li>\n
  • Customized molecular-weight specifications: available<\/li>\n
  • Minimum order quantity: 1 kg<\/li>\n
  • Packaging: 25 kg\/drum<\/li>\n
  • Storage: Keep cool, dry and sealed.<\/li>\n
  • Shelf life: 2 years<\/li>\n
  • Supporting documents: COA, TDS and SDS, plus applicable quality-system and market documents.<\/li>\n<\/ul>\n

    Frequently Asked Questions<\/h2>\n
    \n
    \nDoes a 3\u20135 kDa specification mean the average molecular weight is 4 kDa?<\/summary>\n

    Not necessarily. A 3\u20135 kDa specification is a stated molecular-weight range; it does not, by itself, define an average value or the percentage of material below a threshold. Confirm the measurement format and distribution data when comparing grades.<\/p>\n<\/details>\n

    \nDoes a lower molecular weight automatically mean better absorption and stronger activity?<\/summary>\n

    The product profile describes easier digestion, absorption and utilization, together with stronger related biological activity compared with conventional chondroitin sulfate. However, a lower molecular-weight number alone does not quantify those differences. Review the molecular-weight distribution, structural characterization and supporting activity data for the specific grade.<\/p>\n<\/details>\n

    \nCan assay results from different suppliers be compared directly?<\/summary>\n

    Not by percentage alone. First confirm that the results use the same reporting basis, such as dried basis, and review the assay method and specification definition. Then compare assay alongside molecular-weight profile and other relevant quality parameters.<\/p>\n<\/details>\n

    \nHow should I evaluate this ingredient for a clear beverage?<\/summary>\n

    Start by testing the ingredient at the intended use level in the target aqueous phase. Next, add the full formula, apply the planned processing conditions and check appearance during storage. Observing these stages separately helps identify whether a change begins during dissolution, after other ingredients are added, or during processing and storage.<\/p>\n<\/details>\n<\/div>\n<\/div>","protected":false},"excerpt":{"rendered":"

    Ureda Naturals manufactures Low Molecular Weight Chondroitin Sulfate Sodium powder in a standard 3\u20135 kDa grade, with customized molecular-weight specifications available. The product profile features a narrow molecular-weight distribution, structural characterization and laboratory-verified activity.<\/p>","protected":false},"featured_media":1818,"template":"","meta":[],"product_brand":[],"product_cat":[28],"product_tag":[102,101,100,103,99],"class_list":["post-1816","product","type-product","status-publish","has-post-thumbnail","product_cat-collagen-peptides-joint-health-ingredients","product_tag-chondroitin-sulfate-oligosaccharide","product_tag-chondroitin-sulfate-powder","product_tag-chondroitin-sulfate-sodium","product_tag-joint-health-ingredients","product_tag-low-molecular-weight-chondroitin-sulfate","first","instock","shipping-taxable","product-type-simple"],"yoast_head":"\nLow Molecular Weight Chondroitin Sulfate Sodium | Ureda Naturals<\/title>\n<meta name=\"description\" content=\"Ureda Naturals manufactures low molecular weight chondroitin sulfate sodium powder in a standard 3\u20135 kDa grade, with \u226590% dried-basis assay and 25 kg\/drum 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