{"id":1763,"date":"2026-09-24T16:43:09","date_gmt":"2026-09-24T08:43:09","guid":{"rendered":"https:\/\/uredanaturals.com\/?post_type=product&p=1763"},"modified":"2026-09-24T17:06:19","modified_gmt":"2026-09-24T09:06:19","slug":"pyrroloquinoline-quinone-disodium-salt","status":"publish","type":"product","link":"https:\/\/uredanaturals.com\/es\/producto\/pyrroloquinoline-quinone-disodium-salt\/","title":{"rendered":"Pyrroloquinoline Quinone Disodium Salt (PQQ)"},"content":{"rendered":"

Ureda Naturals is a Pyrroloquinoline Quinone Disodium Salt manufacturer supplying fermentation-derived Pyrroloquinoline Quinone Disodium Salt powder with an assay above 98%. The product is available in three grades: PQQ I dark fine powder, PQQ II light coarse powder and PQQ III light fine powder.<\/p>\n

These grades are designed for different powder-handling and formulation requirements. Selection should consider particle size, color, blending behavior, feeding performance, reconstitution and finished-product appearance\u2014not assay alone.<\/p>\n

Product Identity<\/h2>\n\n\n\n\n\n\n\n\n\n\n\n\n
Item<\/th>\nSpecification<\/th>\n<\/tr>\n<\/thead>\n
Product name<\/th>\nPyrroloquinoline Quinone Disodium Salt<\/td>\n<\/tr>\n
CAS No.<\/th>\n122628-50-6<\/td>\n<\/tr>\n
Molecular formula<\/th>\nC14<\/sub>H4<\/sub>N2<\/sub>Na2<\/sub>O8<\/sub><\/td>\n<\/tr>\n
Molecular weight<\/th>\n374.17 g\/mol<\/td>\n<\/tr>\n
Source<\/th>\nFermentation-derived<\/td>\n<\/tr>\n
Physical form<\/th>\nPowder<\/td>\n<\/tr>\n
Assay<\/th>\n>98%<\/td>\n<\/tr>\n
Available grades<\/th>\nPQQ I, PQQ II and PQQ III<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Pyrroloquinoline Quinone Disodium Salt Grade Options<\/h2>\n\n\n\n\n\n\n\n
Grade<\/th>\nAppearance<\/th>\nParticle form<\/th>\nFormulation focus<\/th>\n<\/tr>\n<\/thead>\n
PQQ I<\/th>\nDark-colored powder<\/td>\nFine<\/td>\nCapsules, tablets and fine premixes<\/td>\n<\/tr>\n
PQQ II<\/th>\nLight-colored powder<\/td>\nCoarse<\/td>\nSolid beverages, sachets and continuous feeding<\/td>\n<\/tr>\n
PQQ III<\/th>\nLight-colored powder<\/td>\nFine<\/td>\nFine powders and formulations with lighter appearance requirements<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

PQQ I: Dark Fine Powder<\/h3>\n

PQQ I is suitable when fine particle distribution and low-dose blending are important. For capsule, tablet and fine premix applications, the main development checks are agglomeration, static charge, segregation and content variation between sampling points.<\/p>\n

PQQ II: Light Coarse Powder<\/h3>\n

PQQ II is suitable when feeding stability, dust control and continuous transfer are important. The coarse particle form can support easier handling, while particle-size compatibility with other premix ingredients should be reviewed to control segregation.<\/p>\n

PQQ III: Light Fine Powder<\/h3>\n

PQQ III combines a lighter appearance with a fine powder form. It is suitable for formulations that require fine dispersion while placing greater emphasis on the visual appearance of the finished product.<\/p>\n

Color, Assay and Particle Size<\/h2>\n

The color of Pyrroloquinoline Quinone Disodium Salt does not directly determine assay or purity. Dark and light grades can meet the same assay requirement, so color should be assessed separately from chemical identity and quality testing.<\/p>\n

For capsules, tablets, solid beverages and clear or lightly colored liquid systems, the selected grade should be tested directly in the target formulation. Powder appearance alone cannot predict the final product color.<\/p>\n

Particle size affects flow, dust, agglomeration, segregation, wetting and blend uniformity. Fine powder can support finer dispersion, while coarse powder can improve handling and feeding performance.<\/p>\n

Fermentation-Derived Production<\/h2>\n

Ureda Naturals Pyrroloquinoline Quinone Disodium Salt is produced through a fermentation-derived route followed by purification, disodium-salt formation, drying, milling and particle-size processing.<\/p>\n\n\n\n\n\n\n\n\n\n
Production factor<\/th>\nFormulation relevance<\/th>\n<\/tr>\n<\/thead>\n
Fermentation and purification<\/th>\nRelated substances, identity and batch consistency<\/td>\n<\/tr>\n
Disodium-salt formation<\/th>\nMolecular basis and water-phase behavior<\/td>\n<\/tr>\n
Drying<\/th>\nMoisture, caking and storage performance<\/td>\n<\/tr>\n
Milling and sieving<\/th>\nFlow, dust, dispersion and blend uniformity<\/td>\n<\/tr>\n
Moisture- and light-barrier packaging<\/th>\nProtection during storage and transport<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

Disodium Salt and Free-Acid Conversion<\/h2>\n

Pyrroloquinoline Quinone Disodium Salt and Pyrroloquinoline Quinone free acid use different molecular-weight bases.<\/p>\n\n\n\n\n\n\n
Form<\/th>\nMolecular formula<\/th>\nMolecular weight<\/th>\n<\/tr>\n<\/thead>\n
Pyrroloquinoline Quinone Disodium Salt<\/th>\nC14<\/sub>H4<\/sub>N2<\/sub>Na2<\/sub>O8<\/sub><\/td>\n374.17<\/td>\n<\/tr>\n
Pyrroloquinoline Quinone free acid<\/th>\nC14<\/sub>H6<\/sub>N2<\/sub>O8<\/sub><\/td>\n330.21<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n
    \n
  • 1 g Pyrroloquinoline Quinone Disodium Salt is approximately equivalent to 0.882 g of free-acid equivalent.<\/li>\n
  • Material with a 98% assay corresponds to approximately 0.865 g of free-acid equivalent per gram.<\/li>\n
  • 98% disodium salt should not be treated as equivalent to 98% free acid.<\/li>\n<\/ul>\n

    Matching the Grade to the Finished Product<\/h2>\n\n\n\n\n\n\n\n\n\n\n
    Finished product<\/th>\nStarting grade<\/th>\nMain process focus<\/th>\nKey evaluation points<\/th>\n<\/tr>\n<\/thead>\n
    Capsules<\/th>\nPQQ I or PQQ III<\/td>\nPremixing, segregation and filling<\/td>\nContent uniformity, fill-weight variation and capsule appearance<\/td>\n<\/tr>\n
    Tablets<\/th>\nPQQ I or PQQ III<\/td>\nPowder flow, mixing and compression<\/td>\nTablet weight, hardness, color distribution and assay uniformity<\/td>\n<\/tr>\n
    Solid beverages<\/th>\nPQQ II or PQQ III<\/td>\nWetting, dispersion and dust control<\/td>\nReconstitution time, caking, sediment and color<\/td>\n<\/tr>\n
    Powder sachets<\/th>\nPQQ II or PQQ III<\/td>\nContinuous feeding and filling<\/td>\nDosage accuracy, powder loss and blend uniformity<\/td>\n<\/tr>\n
    Energy and sports drinks<\/th>\nGrade selected by water-phase testing<\/td>\npH, acid system, heat and light exposure<\/td>\nInitial color, precipitation and assay retention<\/td>\n<\/tr>\n
    Oral liquids<\/th>\nGrade selected by liquid-system testing<\/td>\nAddition order, homogenization and storage<\/td>\nClarity, sediment, color change and assay retention<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

    Pyrroloquinoline Quinone Disodium Salt for Beverages<\/h2>\n

    Initial dispersion does not prove stability throughout beverage processing and storage. The final result depends on the interaction between Pyrroloquinoline Quinone Disodium Salt and the complete liquid system.<\/p>\n

      \n
    • pH and total acidity;<\/li>\n
    • ascorbic acid and organic acids;<\/li>\n
    • minerals and metal ions;<\/li>\n
    • order of addition;<\/li>\n
    • mixing and homogenization;<\/li>\n
    • heat-treatment temperature and holding time;<\/li>\n
    • light and oxygen exposure;<\/li>\n
    • packaging transparency and barrier properties.<\/li>\n<\/ul>\n

      Acidic beverage systems may show color change, precipitation or assay variation even when the beverage appears uniform immediately after mixing. Increasing mixing intensity alone cannot replace complete formulation and storage evaluation.<\/p>\n

      Quality Specification<\/h2>\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
      Test item<\/th>\nSpecification<\/th>\n<\/tr>\n<\/thead>\n
      Appearance<\/th>\nDark-colored or light-colored powder according to grade<\/td>\n<\/tr>\n
      Identification<\/th>\nConforms by HPLC and IR<\/td>\n<\/tr>\n
      Assay, dry basis<\/th>\n>98%<\/td>\n<\/tr>\n
      Moisture<\/th>\n\u226412%<\/td>\n<\/tr>\n
      Particle size<\/th>\nFine-powder reference: \u226599% through 20 mesh; coarse grade follows the selected grade specification<\/td>\n<\/tr>\n
      Ash<\/th>\n\u22641.0%<\/td>\n<\/tr>\n
      Residual ethanol<\/th>\n\u22640.5%<\/td>\n<\/tr>\n
      Total heavy metals<\/th>\n\u226410 ppm<\/td>\n<\/tr>\n
      Lead<\/th>\n\u22640.5 ppm<\/td>\n<\/tr>\n
      Arsenic<\/th>\n\u22641.0 ppm<\/td>\n<\/tr>\n
      Cadmium<\/th>\n\u22641.0 ppm<\/td>\n<\/tr>\n
      Mercury<\/th>\n\u22640.1 ppm<\/td>\n<\/tr>\n
      Total plate count<\/th>\n\u22641,000 CFU\/g<\/td>\n<\/tr>\n
      Yeast and mold<\/th>\n\u2264100 CFU\/g<\/td>\n<\/tr>\n
      Escherichia coli<\/th>\nNot detected<\/td>\n<\/tr>\n
      Salmonella<\/th>\nNot detected<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

      Assay confirms chemical content. Moisture and packaging affect storage performance, particle size affects powder handling and blending, while microbiological and elemental-impurity testing supports finished-product quality control.<\/p>\n

      Packaging, Storage and Quality Documentation<\/h2>\n

      MOQ<\/h3>\n

      Minimum order quantity: 1 kg.<\/p>\n

      Packaging<\/h3>\n
        \n
      • 1 kg, 5 kg or 10 kg bags;<\/li>\n
      • 5 kg, 10 kg or 25 kg paper drums;<\/li>\n
      • inner PE bag;<\/li>\n
      • outer aluminum-foil bag;<\/li>\n
      • paper drum or carton as the outer package.<\/li>\n<\/ul>\n

        Storage<\/h3>\n

        Keep sealed in a cool, dry place away from strong light at room temperature. Reseal the package promptly after opening to reduce moisture, air and light exposure.<\/p>\n

        \"powder<\/p>\n

        \"\"<\/p>\n

        Available Documentation<\/h3>\n
          \n
        • COA;<\/li>\n
        • TDS;<\/li>\n
        • SDS;<\/li>\n
        • GMP;<\/li>\n
        • FSSC 22000;<\/li>\n
        • ISO 9001;<\/li>\n
        • HACCP;<\/li>\n
        • Halal;<\/li>\n
        • Kosher;<\/li>\n
        • FDA\/GRAS-related regulatory documentation;<\/li>\n
        • heavy-metal, microbiological and residue-control documents.<\/li>\n<\/ul>\n
          \"Ureda
          \u00a0<\/figcaption><\/figure>\n

          Frequently Asked Questions<\/h2>\n
          \nWhat is the difference between PQQ I, PQQ II and PQQ III?<\/summary>\n

          PQQ I is a dark fine powder, PQQ II is a light coarse powder and PQQ III is a light fine powder. All three grades have an assay above 98%, but they are selected for different powder-handling and finished-product requirements.<\/p>\n<\/details>\n

          \nDoes the color of Pyrroloquinoline Quinone Disodium Salt indicate its purity?<\/summary>\n

          No. Color should be evaluated separately from assay, identification, related substances and impurity testing. The correct grade depends on the finished-product appearance and processing requirements.<\/p>\n<\/details>\n

          \nWhy does particle size matter when the assay is the same?<\/summary>\n

          Particle size affects flow, dust, agglomeration, segregation and blend uniformity. Fine powder supports finer dispersion, while coarse powder may improve feeding and handling performance.<\/p>\n<\/details>\n

          \nCan the disodium salt be calculated directly as Pyrroloquinoline Quinone free acid?<\/summary>\n

          No. The two forms have different molecular weights. One gram of Pyrroloquinoline Quinone Disodium Salt corresponds to approximately 0.882 g of free-acid equivalent before assay adjustment.<\/p>\n<\/details>\n

          \nIs Pyrroloquinoline Quinone Disodium Salt suitable for acidic beverages?<\/summary>\n

          It can be evaluated for acidic beverage formulations, but pH, organic acids, minerals, metal ions, heat treatment, light and storage must be assessed together. Initial dispersion does not prove long-term beverage stability.<\/p>\n<\/details>\n

          \nWhy can a beverage become darker or develop sediment during storage?<\/summary>\n

          Changes in pH, temperature, light exposure, oxygen exposure and ingredient interactions can alter the liquid system during storage. Color and sediment should be checked before processing, after processing and during storage.<\/p>\n<\/details>\n

          \nWhich quality parameters should be reviewed besides assay?<\/summary>\n

          Quality review should include identification, moisture, particle size, ash, residual ethanol, heavy metals, total plate count, yeast and mold, Escherichia coli and Salmonella. Beverage applications should also include color, clarity, sediment and assay-retention checks.<\/p>\n<\/details>\n

          \nWhich grade is suitable for capsules, tablets or solid beverages?<\/summary>\n

          PQQ I and PQQ III are suitable starting grades for fine powder premixes, capsules and tablets. PQQ II and PQQ III can be evaluated for solid beverages and sachets where feeding, dust control and reconstitution are important.<\/p>\n<\/details>","protected":false},"excerpt":{"rendered":"

          Ureda Naturals is a Pyrroloquinoline Quinone Disodium Salt manufacturer supplying fermentation-derived powder with an assay above 98%. Available in dark fine, light coarse and light fine grades for capsules, tablets, solid beverages, energy drinks, sports drinks and electrolyte formulations.<\/p>","protected":false},"featured_media":1606,"template":"","meta":[],"product_brand":[],"product_cat":[27],"product_tag":[77,75,76,72,73,74],"class_list":["post-1763","product","type-product","status-publish","has-post-thumbnail","product_cat-nutraceutical-functional-ingredients","product_tag-cas-122628-50-6","product_tag-fermentation-derived-ingredients","product_tag-functional-food-ingredients","product_tag-nutraceutical-ingredients","product_tag-pyrroloquinoline-quinone-disodium-salt","product_tag-pyrroloquinoline-quinone-disodium-salt-powder","first","instock","shipping-taxable","product-type-simple"],"yoast_head":"\nPyrroloquinoline Quinone Disodium Salt Manufacturer | Ureda Naturals<\/title>\n<meta name=\"description\" content=\"Ureda Naturals manufactures fermentation-derived Pyrroloquinoline Quinone Disodium Salt powder 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