{"id":1351,"date":"2026-09-16T11:27:33","date_gmt":"2026-09-16T03:27:33","guid":{"rendered":"https:\/\/uredanaturals.com\/?post_type=product&p=1351"},"modified":"2026-09-24T10:42:34","modified_gmt":"2026-09-24T02:42:34","slug":"l-glutathione-reduced","status":"publish","type":"product","link":"https:\/\/uredanaturals.com\/es\/producto\/l-glutathione-reduced\/","title":{"rendered":"L-Glutathione Reduced"},"content":{"rendered":"

L-Glutathione Reduced for Food and Cosmetic Formulation<\/h2>\n

L-Glutathione Reduced is a white crystalline powder supplied by Ureda Naturals for dietary supplements, functional foods and cosmetic formulations. The product is available in Food Grade and Cosmetic Grade, with a documented assay range of 98.0\u2013102.0% on a dry basis.<\/p>\n

The two grades share the same core chemical identity, but their intended use, documentation focus and formulation requirements are different. Selecting the correct grade at the beginning of development helps keep the raw material, finished-product process and quality documentation aligned.<\/p>\n

Choose the Grade by the Finished Product<\/h2>\n
\n\n\n\n\n\n\n
Grade<\/th>\nTypical finished products<\/th>\nMain quality focus<\/th>\n<\/tr>\n<\/thead>\n
Food Grade<\/strong><\/td>\nCapsules, tablets, sachets, powder blends and functional food systems<\/td>\nAssay, identity, related substances, moisture, elemental impurities and microbiological quality<\/td>\n<\/tr>\n
Cosmetic Grade<\/strong><\/td>\nSerums, gels, creams, masks and other topical formulations<\/td>\nIdentity, assay, solution behavior, moisture, related substances and microbiological quality<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

Both grades are supplied as L-Glutathione Reduced powder. The correct selection should be based on the intended finished product, processing conditions, quality specifications and regulatory documentation required for the destination market.<\/p>\n

Product Identity and Core Specifications<\/h2>\n
\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Parameter<\/th>\nSpecification<\/th>\n<\/tr>\n<\/thead>\n
Product name<\/td>\nL-Glutathione Reduced<\/td>\n<\/tr>\n
CAS number<\/td>\n70-18-8<\/td>\n<\/tr>\n
Molecular formula<\/td>\nC10<\/sub>H17<\/sub>N3<\/sub>O6<\/sub>S<\/td>\n<\/tr>\n
Molecular weight<\/td>\n307.32 g\/mol<\/td>\n<\/tr>\n
Appearance<\/td>\nWhite crystalline powder<\/td>\n<\/tr>\n
Water solubility<\/td>\nFreely soluble in water<\/td>\n<\/tr>\n
Assay<\/td>\n98.0\u2013102.0% on a dry basis<\/td>\n<\/tr>\n
Oxidized glutathione<\/td>\nNot more than 1.5%<\/td>\n<\/tr>\n
Total related substances<\/td>\nNot more than 2.0%<\/td>\n<\/tr>\n
Loss on drying<\/td>\nNot more than 0.5%<\/td>\n<\/tr>\n
Shelf life<\/td>\n36 months under the stated storage conditions<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

<\/h2>\n

Food Grade COA Parameters<\/h2>\n

The following table presents the Food Grade COA parameters and tested results supplied for L-Glutathione Reduced.<\/p>\n

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Test item<\/th>\nSpecification<\/th>\nResult<\/th>\n<\/tr>\n<\/thead>\n
Appearance<\/td>\nWhite crystalline powder<\/td>\nWhite crystalline powder<\/td>\n<\/tr>\n
Solubility<\/td>\nFreely soluble in water; very slightly soluble in ethanol and methylene chloride<\/td>\nComplies<\/td>\n<\/tr>\n
Assay<\/td>\n98.0\u2013102.0% on dry basis<\/td>\n99.4%<\/td>\n<\/tr>\n
Optical rotation<\/td>\n\u221215.5\u00b0 to \u221217.5\u00b0<\/td>\n\u221216.7\u00b0<\/td>\n<\/tr>\n
Bulk density<\/td>\nNot less than 0.20 g\/mL<\/td>\n0.38 g\/mL<\/td>\n<\/tr>\n
Tapped density<\/td>\nNot less than 0.40 g\/mL<\/td>\n0.62 g\/mL<\/td>\n<\/tr>\n
Identification by IR<\/td>\nMatches the reference spectrum<\/td>\nComplies<\/td>\n<\/tr>\n
Clarity and colour of solution<\/td>\nClear and colourless<\/td>\nComplies<\/td>\n<\/tr>\n
Chlorides<\/td>\nNot more than 0.02%<\/td>\n<0.02%<\/td>\n<\/tr>\n
Sulfates<\/td>\nNot more than 0.03%<\/td>\n<0.03%<\/td>\n<\/tr>\n
Ammonium<\/td>\nNot more than 0.02%<\/td>\n<0.02%<\/td>\n<\/tr>\n
Iron<\/td>\nNot more than 0.001%<\/td>\n<0.001%<\/td>\n<\/tr>\n
Loss on drying<\/td>\nNot more than 0.5%<\/td>\n0.1%<\/td>\n<\/tr>\n
Residue on ignition<\/td>\nNot more than 0.1%<\/td>\n0.08%<\/td>\n<\/tr>\n
Heavy metals<\/td>\nNot more than 10 ppm<\/td>\n<10 ppm<\/td>\n<\/tr>\n
Arsenic<\/td>\nNot more than 1 ppm<\/td>\n<1 ppm<\/td>\n<\/tr>\n
Lead<\/td>\nNot more than 2 ppm<\/td>\n<2 ppm<\/td>\n<\/tr>\n
Mercury<\/td>\nNot more than 0.2 ppm<\/td>\n<0.2 ppm<\/td>\n<\/tr>\n
Cadmium<\/td>\nNot more than 0.3 ppm<\/td>\n<0.3 ppm<\/td>\n<\/tr>\n
Oxidized glutathione<\/td>\nNot more than 1.5%<\/td>\n0.41%<\/td>\n<\/tr>\n
Total related substances<\/td>\nNot more than 2.0%<\/td>\n0.53%<\/td>\n<\/tr>\n
Total plate count<\/td>\nNot more than 1,000 CFU\/g<\/td>\n<10 CFU\/g<\/td>\n<\/tr>\n
Coliforms<\/td>\nNot more than 100 CFU\/g<\/td>\n<10 CFU\/g<\/td>\n<\/tr>\n
Yeast and mold<\/td>\nNot more than 50 CFU\/g<\/td>\n<10 CFU\/g<\/td>\n<\/tr>\n
Salmonella<\/td>\nNot detected<\/td>\nNot detected<\/td>\n<\/tr>\n
Staphylococcus aureus<\/td>\nNot detected<\/td>\nNot detected<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

<\/h2>\n

Cosmetic Grade COA Parameters<\/h2>\n

The following table presents the Cosmetic Grade COA parameters and tested results supplied for L-Glutathione Reduced.<\/p>\n

\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n\n
Test item<\/th>\nSpecification<\/th>\nResult<\/th>\n<\/tr>\n<\/thead>\n
Appearance<\/td>\nWhite crystalline powder<\/td>\nWhite crystalline powder<\/td>\n<\/tr>\n
Solubility<\/td>\nFreely soluble in water; very slightly soluble in ethanol and methylene chloride<\/td>\nComplies<\/td>\n<\/tr>\n
Assay<\/td>\n98.0\u2013102.0% on dry basis<\/td>\n99.3%<\/td>\n<\/tr>\n
Optical rotation<\/td>\n\u221215.5\u00b0 to \u221217.5\u00b0<\/td>\n\u221216.3\u00b0<\/td>\n<\/tr>\n
Bulk density<\/td>\nNot less than 0.20 g\/mL<\/td>\n0.39 g\/mL<\/td>\n<\/tr>\n
Tapped density<\/td>\nNot less than 0.40 g\/mL<\/td>\n0.66 g\/mL<\/td>\n<\/tr>\n
Identification by IR<\/td>\nMatches the reference spectrum<\/td>\nComplies<\/td>\n<\/tr>\n
Clarity and colour of solution<\/td>\nClear and colourless<\/td>\nComplies<\/td>\n<\/tr>\n
Chlorides<\/td>\nNot more than 0.02%<\/td>\n<0.02%<\/td>\n<\/tr>\n
Sulfates<\/td>\nNot more than 0.03%<\/td>\n<0.03%<\/td>\n<\/tr>\n
Ammonium<\/td>\nNot more than 0.02%<\/td>\n<0.02%<\/td>\n<\/tr>\n
Iron<\/td>\nNot more than 0.001%<\/td>\n<0.001%<\/td>\n<\/tr>\n
Loss on drying<\/td>\nNot more than 0.5%<\/td>\n0.1%<\/td>\n<\/tr>\n
Residue on ignition<\/td>\nNot more than 0.1%<\/td>\n0.1%<\/td>\n<\/tr>\n
Heavy metals<\/td>\nNot more than 10 ppm<\/td>\n<10 ppm<\/td>\n<\/tr>\n
Arsenic<\/td>\nNot more than 1 ppm<\/td>\n<1 ppm<\/td>\n<\/tr>\n
Lead<\/td>\nNot more than 2 ppm<\/td>\n<2 ppm<\/td>\n<\/tr>\n
Mercury<\/td>\nNot more than 0.2 ppm<\/td>\n<0.2 ppm<\/td>\n<\/tr>\n
Cadmium<\/td>\nNot more than 0.3 ppm<\/td>\n<0.3 ppm<\/td>\n<\/tr>\n
Oxidized glutathione<\/td>\nNot more than 1.5%<\/td>\n0.29%<\/td>\n<\/tr>\n
Total related substances<\/td>\nNot more than 2.0%<\/td>\n0.55%<\/td>\n<\/tr>\n
Total plate count<\/td>\nNot more than 1,000 CFU\/g<\/td>\n<10 CFU\/g<\/td>\n<\/tr>\n
Coliforms<\/td>\nNot more than 100 CFU\/g<\/td>\n<10 CFU\/g<\/td>\n<\/tr>\n
Yeast and mold<\/td>\nNot more than 50 CFU\/g<\/td>\n<10 CFU\/g<\/td>\n<\/tr>\n
Salmonella<\/td>\nNot detected<\/td>\nNot detected<\/td>\n<\/tr>\n
Staphylococcus aureus<\/td>\nNot detected<\/td>\nNot detected<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

Why Assay Alone Does Not Define L-Glutathione Reduced Quality<\/h2>\n

Assay measures the amount of L-Glutathione Reduced on a dry basis, but it does not describe every quality attribute that influences formulation performance. A complete technical review should read assay together with optical rotation, infrared identity, oxidized glutathione, total related substances, loss on drying, residue on ignition, elemental impurities and microbiological results.<\/p>\n

The reduced form contains a reactive thiol group. During storage or processing, oxygen exposure, light, moisture, temperature and the surrounding formulation can influence the balance between reduced and oxidized material. This is why two powders with similar assay values can behave differently after being dissolved or incorporated into a finished product.<\/p>\n

FDA analytical work on glutathione has also emphasized the need to evaluate the parent compound and related impurities with a validated chromatographic method rather than relying on a single assay result.<\/p>\n

<\/h2>\n

Food Grade Processing Considerations<\/h2>\n

Dry-dose products<\/h3>\n

For capsules, tablets, sachets and dry blends, the main process questions are powder flow, bulk density, blend uniformity and moisture exposure. Bulk density and tapped density help the formulator estimate fill volume and select a practical blending and filling sequence.<\/p>\n

L-Glutathione Reduced should be introduced into a dry blend after the major carrier ingredients have been de-lumped. Excessive residence time in an open mixing environment can increase exposure to humidity and oxygen. The final blend should be evaluated for assay uniformity, moisture, flow behavior and packaging compatibility.<\/p>\n

Functional food and beverage systems<\/h3>\n

When L-Glutathione Reduced is dissolved into a liquid system, the development focus changes from powder handling to solution stability. The development batch should monitor dissolution time, clarity, colour, pH, dissolved oxygen exposure and assay retention during the intended holding period.<\/p>\n

A clear solution at the time of manufacture does not by itself demonstrate long-term reduced-state retention. The finished beverage or liquid supplement should be evaluated under its actual container, filling temperature, headspace and storage conditions.<\/p>\n

<\/h2>\n

Cosmetic Grade Processing Considerations<\/h2>\n

Cosmetic Grade L-Glutathione Reduced can be evaluated in serums, gels, creams, masks and other topical systems. The most important development variables are the formula pH range, water activity, oxygen exposure, light exposure, preservative system, metal-ion environment and the temperature history of the batch.<\/p>\n

For aqueous products, prepare the required solution under controlled mixing and add it at the process stage that limits unnecessary heat and oxygen exposure. For emulsions, the addition point should be selected according to the validated cool-down and homogenization sequence of the individual formula.<\/p>\n

Finished-product testing should include appearance, colour, odour, pH, viscosity where applicable, assay retention and oxidized glutathione or related-substance monitoring over the intended shelf-life study.<\/p>\n

<\/h2>\n

Packaging, Storage and Shelf Life<\/h2>\n
\n\n\n\n\n\n\n\n\n\n\n\n
Item<\/th>\nUreda Naturals supply information<\/th>\n<\/tr>\n<\/thead>\n
Minimum order quantity<\/td>\n1 kg<\/td>\n<\/tr>\n
Bag packing<\/td>\n1 kg, 5 kg or 10 kg per bag<\/td>\n<\/tr>\n
Drum packing<\/td>\n5 kg, 10 kg or 25 kg per paper drum<\/td>\n<\/tr>\n
Inner packaging<\/td>\nOne PE bag with an outer aluminum-foil bag<\/td>\n<\/tr>\n
Outer packaging<\/td>\nPaper drum for drum packing or carton for bag packing<\/td>\n<\/tr>\n
Storage<\/td>\nKeep sealed in a cool and dry place, away from strong light, heat and unnecessary air exposure<\/td>\n<\/tr>\n
Shelf life<\/td>\n36 months under the stated storage conditions<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n<\/div>\n

\"L-Glutathione<\/p>\n

\"powder<\/p>\n

Certifications and Quality Documentation<\/h2>\n
\n\n\n\n\n\n\n\n\n
Documentation category<\/th>\nAvailable documentation<\/th>\n<\/tr>\n<\/thead>\n
Quality and manufacturing systems<\/td>\nGMP, FSSC 22000, ISO 9001 and HACCP<\/td>\n<\/tr>\n
Religious certifications<\/td>\nHalal and Kosher<\/td>\n<\/tr>\n
Product quality documents<\/td>\nFood Grade COA, Cosmetic Grade COA, TDS and SDS<\/td>\n<\/tr>\n
Regulatory support<\/td>\nFDA or\u00a0 GRAS<\/td>\n<\/tr>\n<\/tbody>\n<\/table>\n

 <\/p>\n<\/div>\n

\"Ureda<\/p>\n

<\/h2>\n

Frequently Asked Questions<\/h2>\n
\n
\nWhy does a 99% assay not fully define L-Glutathione Reduced quality?<\/summary>\n

Assay describes the amount of L-Glutathione Reduced on a dry basis. It should be read together with identity, oxidized glutathione, total related substances, moisture, elemental impurities and microbiological quality.<\/p>\n<\/details>\n

\nWhat do oxidized glutathione and total related substances indicate?<\/summary>\n

Oxidized glutathione indicates the amount of material that has changed from the reduced state, while total related substances describe the broader impurity profile measured by the test method.<\/p>\n<\/details>\n

\nWhy can a clear solution still lose reduced glutathione during storage?<\/summary>\n

Clarity only describes the visible state of the solution. Oxygen, light, temperature, pH, trace metals, container headspace and holding time can still affect chemical stability.<\/p>\n<\/details>\n

\nHow should Food Grade and Cosmetic Grade be selected?<\/summary>\n

Food Grade is intended for dietary supplements and functional food applications. Cosmetic Grade is intended for serums, gels, creams, masks and other topical formulations.<\/p>\n<\/details>\n

\nHow should L-Glutathione Reduced be handled in capsules, tablets and dry blends?<\/summary>\n

Review bulk density, tapped density, moisture and blend uniformity before finalizing the filling process. Limit unnecessary exposure to humidity and air during blending.<\/p>\n<\/details>\n

\nWhat should be checked when developing a beverage or liquid supplement?<\/summary>\n

Evaluate dissolution time, clarity, colour, pH, dissolved oxygen exposure, container headspace and assay retention under actual filling and storage conditions.<\/p>\n<\/details>\n

\nHow should Cosmetic Grade L-Glutathione Reduced be added to a serum, gel or cream?<\/summary>\n

Select the addition point according to the formula pH, temperature, mixing and homogenization sequence. Monitor appearance, pH, assay retention and related substances during stability testing.<\/p>\n<\/details>\n

\nCan Food Grade L-Glutathione Reduced be used to compound injectable products?<\/summary>\n

No. Food Grade is intended for food and dietary supplement applications. Injectable development requires a separately qualified pharmaceutical-grade material with controls for sterility, endotoxin, impurities and aseptic processing.<\/p>\n<\/details>\n<\/div>","protected":false},"excerpt":{"rendered":"

Ureda Naturals manufactures Food Grade and Cosmetic Grade L-Glutathione Reduced Powder (GSH), CAS 70-18-8, for bulk nutraceutical and formulation projects. Supplied as a white crystalline powder with a 98.0\u2013102.0% assay range on a dried basis, it is available in 1 kg, 5 kg, 10 kg, 20 kg and 25 kg pack sizes with batch COA and QA documentation for qualification.<\/p>","protected":false},"featured_media":1360,"template":"","meta":[],"product_brand":[34],"product_cat":[27],"product_tag":[43,52,42,51,41,40,50,53,39,54],"class_list":["post-1351","product","type-product","status-publish","has-post-thumbnail","product_brand-ureda-naturals","product_cat-nutraceutical-functional-ingredients","product_tag-cas-70-18-8","product_tag-cosmetic-grade-l-glutathione-reduced","product_tag-food-grade","product_tag-food-grade-l-glutathione-reduced","product_tag-gsh","product_tag-l-glutathione-reduced","product_tag-l-glutathione-reduced-manufacturer","product_tag-l-glutathione-reduced-powder","product_tag-reduced-glutathione","product_tag-reduced-glutathione-coa","first","instock","shipping-taxable","product-type-simple"],"yoast_head":"\nL-Glutathione Reduced Manufacturer | Ureda Naturals<\/title>\n<meta name=\"description\" content=\"Ureda Naturals manufactures Food Grade and Cosmetic Grade L-Glutathione Reduced (GSH) powder with 98.0\u2013102.0% dry-basis assay and batch COA support.\" \/>\n<meta name=\"robots\" content=\"noindex, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<meta property=\"og:locale\" content=\"es_ES\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"L-Glutathione Reduced\" \/>\n<meta property=\"og:description\" content=\"Ureda Naturals manufactures Food Grade and Cosmetic Grade L-Glutathione Reduced (GSH) powder with 98.0\u2013102.0% dry-basis assay and batch COA support.\" \/>\n<meta property=\"og:url\" content=\"https:\/\/uredanaturals.com\/es\/producto\/l-glutathione-reduced\/\" \/>\n<meta property=\"og:site_name\" content=\"Ureda Naturals\" \/>\n<meta property=\"article:modified_time\" content=\"2026-09-24T02:42:34+00:00\" 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