Cartilage Extract (Type II Collagen)

A hydrolyzed chicken sternal cartilage extract with ≥25% acid mucopolysaccharides, ≥55% protein and ≥4.5% hydroxyproline for joint nutrition formulations.

Additional information

Source

Chicken sternal cartilage

Form

White to light-yellow powder

Protein

≥55% on a dry basis

Acid mucopolysaccharides

≥25%

Particle size

100% through 40 mesh

Packaging

15 kg/drum

Ureda Naturals Cartilage Extract (Type II Collagen) is a hydrolyzed chicken sternal cartilage ingredient standardized to ≥25% acid mucopolysaccharides, ≥55% protein and ≥4.5% hydroxyproline on a dry basis. Supplied as a white to light-yellow powder for joint nutrition and functional food formulations.

  • Chicken sternal cartilage source
  • 100% through 40 mesh; bulk density ≥0.18 g/mL
  • 15 kg/drum; 1 kg MOQ

Hydrolyzed Chicken Sternal Cartilage Extract

Ureda Naturals Cartilage Extract (Type II Collagen) is made from chicken sternal cartilage through hydrolysis, decolorization, nanofiltration, concentration and spray drying. The resulting powder combines cartilage-derived protein, acid mucopolysaccharides and collagen-associated components in one ingredient.

This composition makes it a practical option for joint nutrition formulas that call for a cartilage-derived matrix. Its quality profile is defined by acid mucopolysaccharides, protein and hydroxyproline, alongside physical, chemical and microbiological specifications.

How to Evaluate the Cartilage Matrix

Protein, acid mucopolysaccharides and hydroxyproline answer different quality questions. Reviewing them together gives formulators a more useful composition profile than relying on a product name or a single percentage.

  • Acid mucopolysaccharides ≥25%: defines a key cartilage-associated fraction. It should not automatically be interpreted as an equivalent percentage of chondroitin sulfate.
  • Protein ≥55% on a dry basis: sets the minimum overall protein content. Protein alone does not quantify intact Type II collagen.
  • Hydroxyproline ≥4.5% on a dry basis: provides a collagen-associated analytical marker. It is not, by itself, a direct assay of intact Type II collagen.

When comparing suppliers, confirm that the analytical definitions, units and reporting basis match. A higher protein result alone does not establish a better cartilage extract if the mucopolysaccharide fraction, hydroxyproline, moisture, ash or powder-handling characteristics differ.

Choosing Between Cartilage Extract and Other Collagen Formats

Ingredient format Main quality focus Formulation consideration
Cartilage Extract (Type II Collagen) Acid mucopolysaccharides, protein and hydroxyproline Cartilage-derived matrix for multi-component joint nutrition formulas
Undenatured Type II Collagen Preserved native structure measured with a structure-specific method Different ingredient format and quality definition
Conventional collagen peptides Protein or collagen content and peptide profile Often selected for higher-protein applications
Purified chondroitin sulfate Chondroitin-specific assay Used when the formula requires a defined chondroitin sulfate contribution

These formats should not be substituted kilogram for kilogram without recalculating the formula. Changing the ingredient changes the protein and mucopolysaccharide contribution, powder volume and finished-product composition.

Product Specification and Batch Results

Test item Specification Result
Color White or light yellow Pass
Taste and odor Characteristic Pass
Condition No visible foreign matter Pass
Protein, dry basis ≥55.0 g/100 g 70.4 g/100 g
Acid mucopolysaccharides ≥25.0 g/100 g 26.5 g/100 g
Fat ≤2.0 g/100 g 0.2 g/100 g
Hydroxyproline, dry basis ≥4.5 g/100 g 5.6 g/100 g
Loss on drying ≤5.0 g/100 g 4.6 g/100 g
Ash ≤10.0 g/100 g 9.5 g/100 g
Particle size 100% through 40 mesh Pass
Bulk density ≥0.18 g/mL 0.35 g/mL
Lead ≤0.5 mg/kg <0.5 mg/kg
Cadmium ≤0.1 mg/kg <0.1 mg/kg
Chromium ≤2.0 mg/kg <2.0 mg/kg
Arsenic ≤0.5 mg/kg <0.5 mg/kg
Mercury ≤0.3 mg/kg <0.3 mg/kg
Total bacterial count ≤1,000 CFU/g 100 CFU/g
Yeast and mold ≤25 CFU/g <10 CFU/g
Coliform bacteria ≤0.3 MPN/g <0.3 MPN/g
Salmonella Negative Negative
Staphylococcus aureus Negative Negative

What the Powder Specifications Mean in Production

Attribute Why it matters to the formulator What to check during a trial
100% through 40 mesh Sets an upper particle-size boundary, but does not describe the full particle-size distribution or guarantee blend uniformity. Check blend uniformity, discharge behavior and segregation against the other formula ingredients.
Bulk density ≥0.18 g/mL; result 0.35 g/mL Powder volume affects capsule capacity and can differ substantially from dense minerals or crystalline ingredients. Calculate the volume of the complete blend and check capsule fill-weight variation in a pilot run.
Loss on drying ≤5.0% Moisture uptake can increase cohesion and agglomeration, affecting weighing and flow before a major visual change appears. Observe flow after handling and reseal opened drums promptly, especially in humid production areas.
Ash ≤10.0% Inorganic residue contributes to total formula solids and can matter in mineral-sensitive or clear beverage systems. Account for the ingredient in the solids balance and assess the complete formula rather than the raw material alone.

Application and Process Considerations

Capsules and dry blends

In formulas containing glucosamine salts, minerals or other dense ingredients, differences in bulk density can promote segregation during transfer and discharge. Prepare a geometric premix with a compatible portion of the blend before adding it to the main blender. Confirm uniformity using samples from multiple locations and discharge points.

For capsule development, calculate fill volume from the complete blend rather than from ingredient weights alone. Monitor hopper flow, capsule-weight variation and blend behavior after production stops and restarts.

Tablets

Evaluate flow, compactability and disintegration together. Increasing compression force may improve hardness but delay disintegration; excessive lubricant may weaken tablet bonding. A pilot should therefore measure tablet weight variation, hardness, friability and disintegration as a combined performance profile.

Sachets and powdered beverages

The powder’s water-soluble format supports development in water-based products, while the complete formula determines final turbidity, sediment and sensory performance. Acids, minerals, proteins and hydrocolloids can change how the ingredients hydrate and disperse.

For a beverage pilot, add the powder gradually into a moving water phase, then introduce the other ingredients in the intended process order. Check dispersion time, visible agglomeration, turbidity, sediment after the planned holding period and redispersibility after heat treatment where applicable.

Functional foods

Evaluate the ingredient in the actual food matrix and thermal process. The pilot should confirm sensory profile, dispersion, finished-product appearance and the quality attributes that matter for the intended format.

From Pilot Trial to Commercial Specification

  1. Confirm ingredient identity: align the chicken sternal cartilage source, hydrolyzed format and agreed composition specifications.
  2. Calculate formula contribution: use the acid mucopolysaccharide, protein and hydroxyproline specifications separately; do not convert one result into another ingredient claim.
  3. Run the intended manufacturing process: test the actual capsule, tablet, sachet or beverage process rather than relying only on a raw-material dispersion test.
  4. Measure finished-product performance: select tests relevant to the dosage form, such as blend uniformity, capsule fill variation, tablet disintegration, beverage sediment or sensory profile.
  5. Set the commercial controls: align the raw-material specification, finished-product composition and production checks before scale-up.

Packaging, Storage and Quality Documentation

  • MOQ: 1 kg
  • Standard packaging: 15 kg/drum
  • Shelf life: 24 months
  • Storage: Keep sealed in a cool, dry place and protect from moisture and direct light.
  • Product documents: COA, TDS and SDS
  • Quality and certification documentation: GMP, FSSC 22000, ISO 9001, HACCP, Halal and Kosher

Frequently Asked Questions

Does ≥25% acid mucopolysaccharides mean ≥25% chondroitin sulfate?

No. Acid mucopolysaccharides are a broader analytical category. A chondroitin sulfate declaration requires a suitable chondroitin-specific test and a defined reporting basis. The acid mucopolysaccharide result should not be relabeled as chondroitin sulfate.

Does the protein result represent the amount of Type II collagen?

No. Protein measures the overall protein fraction and does not identify every protein as Type II collagen. Review the cartilage source, protein, acid mucopolysaccharides and hydroxyproline together, and use a specific collagen assay when a quantified Type II collagen claim is required.

How do I calculate the ingredient’s contribution to a formula?

Multiply the planned raw-material amount by the relevant specification separately. At the minimum specification, the ingredient contributes at least 25% acid mucopolysaccharides and 55% protein on a dry basis. Do not use the acid mucopolysaccharide value as a chondroitin sulfate amount or the protein value as a pure Type II collagen amount.

Can this ingredient replace undenatured Type II collagen or conventional collagen peptides?

Not by equal weight. Cartilage Extract (Type II Collagen) is a hydrolyzed cartilage matrix standardized by its composition profile. Undenatured Type II collagen is defined by retention of native structure, while conventional collagen peptides are generally specified around protein or collagen content and peptide profile. Recalculate the formula and validate the finished format after a substitution.

Why can capsule filling vary when the powder passes 40 mesh?

Passing 40 mesh controls oversized particles but does not define the full particle-size distribution, flow or density match with other ingredients. Check the complete blend’s bulk and tapped density, premix quality, hopper flow and capsule-weight variation during a representative pilot run.

What should I check if the powder forms lumps in a beverage?

First check the addition method. Gradual addition into a moving liquid phase can reduce surface-wetted agglomerates that trap dry powder. If lumps persist, assess water temperature, mixing energy, mineral load and the order of acid, protein or hydrocolloid addition in the complete formula.

Can it be used in a clear beverage?

It can be evaluated in water-based products, but clarity must be confirmed in the complete formula. Proteins, acid mucopolysaccharides, minerals, acids and thermal treatment can affect turbidity or sediment. Test the actual formula after processing and the intended holding period.

Which parameters should I compare before changing suppliers?

Compare source tissue, hydrolyzed or undenatured format, acid mucopolysaccharides, protein, hydroxyproline, fat, moisture, ash, particle size, bulk density, heavy metals and microbiology. Confirm that the methods, units and reporting basis match before treating two specifications as equivalent.

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